David Sinclair, Ph.D.
Venture Partner
Dr. Sinclair is a Venture Partner with Lux Capital. He is also Co-Founder of both Sirtris Pharmaceuticals (NASDAQ: SIRT) and Genocea Biosciences, and is Associate Professor of Pathology at Harvard Medical School and Director of the Glenn Laboratories for the Biological Mechanisms of Aging. He has made key contributions to the scientific understanding of aging, making him one of the most highly published and respected scientists in biology. In 1997, Dr. Sinclair identified the cause of aging in yeast, a first for any species, and in 2003 reported the discovery of a conserved master regulatory gene controlling this process. His laboratory at Harvard is currently focused on slowing diseases of aging in mammals using genetic and pharmacological means. In 2004, Dr. Sinclair co-founded Sirtris Pharmaceuticals and helped grow it into one of the most successful biotech companies in recent years. Dr. Sinclair has authored over 50 peer-reviewed scientific publications, including several seminal papers in Nature, Cell and Science. His work has been reported in most of the leading news media including the Wall Street Journal, New York Times, TIME and Newsweek. He has received numerous awards and honors for his research. Dr. Sinclair performed his post-doctoral work with Dr. Leonard Guarente at MIT and holds a Ph.D. in Biochemistry and Molecular Genetics from the University of New South Wales, Australia. Dr. Sinclair was honored by Genzyme with the Outstanding Achievement in Biomedical Science Award for 2004. Dr. Sinclair will remain an Associate Professor at Harvard Medical School and is currently a Director at Sirtris Pharmaceuticals.
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